TUESDAY, Nov. 4, 2014 (HealthDay News) — Residents of a southern United States might be during risk for a parasitic infection that can lead to critical heart illness and death, 3 new studies suggest.
Chagas disease, that is transmitted by “kissing bugs” that feed on a faces of humans during night, was once suspicion singular to Mexico, Central America and South America.
That’s no longer a case, a new investigate shows.
“We are anticipating new justification that locally acquired tellurian delivery is occurring in Texas,” pronounced Melissa Nolan Garcia, a investigate associate during Baylor College of Medicine in Houston and a lead author of dual of a 3 studies.
Garcia is endangered that a series of putrescent people in a United States is flourishing and distant exceeds a U.S. Centers for Disease Control and Prevention’s guess of 300,000.
In one commander study, her group looked during 17 blood donors in Texas who tested certain for a bug that causes Chagas disease.
“We were astounded to find that 36 percent had justification of being a locally acquired case,” she said. “Additionally, 41 percent of this presumably healthy blood donor race had heart abnormalities unchanging with Chagas cardiac disease.”
The CDC, however, still believes many people with a illness in a United States were putrescent in Mexico, Central and South America, pronounced Dr. Susan Montgomery, of a agency’s parasitic diseases branch.
“There have been a few reports of people apropos putrescent with these bugs here in a United States,” she said. “We don’t know how mostly that is function given there might be cases that are undiagnosed, given many doctors would not cruise to exam their patients for this disease. However, we trust a risk of infection is really low.”
Maybe so, though kissing bugs — blood-sucking insects called triatomine bugs — are found opposite a reduce half of a United States, according to a CDC. The insects feed on animals and people during night.
The feces of putrescent bugs contains a bug Trypanosoma cruzi, that can enter a physique by breaks in a skin. Chagas illness can also be transmitted by blood.
It’s a wordless killer, Garcia said. People don’t feel sick, so they don’t find care, though it causes heart illness in about 30 percent of those who get infected, she said.
In another study, Garcia’s group collected 40 insects in 11 Texas counties. They found that 73 percent carried a bug and half of those had bitten humans as good as other animals, such as dogs, rabbits and raccoons.
A third investigate found that many people putrescent with Chagas aren’t treated.
For that project, Dr. Jennifer Manne-Goehler, a clinical associate during Harvard Medical School and Beth Israel Deaconess Medical Center in Boston, collected information on scarcely 2,000 people whose blood tested certain for Chagas.
Her group found that usually 422 doses of remedy for a infection were given by a CDC from 2007 to 2013. “This highlights an huge diagnosis gap,” Manne-Goehler pronounced in a news release.
The commentary of all 3 studies, published recently in a American Journal of Tropical Medicine and Hygiene, were to be presented Tuesday in New Orleans during a annual assembly of a American Society of Tropical Medicine and Hygiene.
Symptoms of Chagas can operation from nothing to critical with fever, fatigue, physique aches and critical cardiac and abdominal complications.
“Physicians should cruise Chagas when patients have flourishing and increase of a heart not caused by high blood pressure, diabetes or other causes, even if they do not have a story of travel,” Garcia said.
However, a dual treatments for this illness are “only accessible [in a United States] around an inquisitive drug custom regulated by a CDC,” Garcia said. They are not nonetheless authorized by a Food and Drug Administration.
Efforts are underneath approach to rise other treatments for Chagas disease, Montgomery said.
“Several groups have done some sparkling swell in drug development,” she said, “but nothing have reached a indicate where they can be used to provide patients in unchanging clinical practice.”
For some-more about Chagas disease, revisit a U.S. Centers for Disease Control and Prevention.
SOURCES: Melissa Nolan Garcia, M.P.H., investigate associate, Baylor College of Medicine, Houston; Susan Montgomery, D.V.M., M.P.H., epidemiology group lead, parasitic diseases branch, U.S. Centers for Disease Control and Prevention; Nov. 4, 2014, presentation, American Society of Tropical Medicine and Hygiene annual meeting, New Orleans; Sept. 29, 2014, American Journal of Tropical Medicine and Hygiene, online
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